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Liver Cancer Treatment – Know The Facts

On the day of treatment, the patient is given a mild sedative and pain medication. The radiologist makes a tiny incision in the groinno larger than the tip of a pencilto gain access to the femoral artery. Using moving X-ray images (fluoroscopy) as a visual guide, the physician directs a thin, flexible tube (catheter) through the artery and into the main blood vessel feeding the liver tumor. The radioactive beads are injected and carried in the bloodstream up to the tumor, where they embed and slowly kill the cancerous cells.

Hepatocellular cancer is more likely to develop in people with chronic cirrhosis. Your specialist may suggest a liver transplant if you have cirrhosis of the liver because of previous liver disease, infection with a hepatitis virus or from drinking alcohol. You will only benefit from a liver transplant if you have a single liver tumour that is less than 5cm across, or up to 3 tumours all less than 3cm across. There is an added difficulty of having to wait for a suitable donor. This can take months. During this delay, the cancer will continue to grow and you have other treatment to try to control it.

Radiofrequency ablation procedure, electric current in the radiofrequency range is used to destroy malignant cells. Using an ultrasound or CT scan as a guide, your surgeon inserts several thin needles into small incisions in your abdomen. When the needles reach the tumor, they’re heated with an electric current, destroying the malignant cells. Radiofrequency ablation is an option for people with small, unresectable hepatocellular tumors and for some types of metastatic liver cancers. Although the procedure has a somewhat higher risk of serious complications than alcohol injection does, it appears to provide better outcomes.

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Treatment of liver cancer may involve surgery, interventional radiological procedures, and chemotherapy or radiation therapy. Individual treatment depends largely on the type and extent of disease.

Alcohol injection. In this procedure, pure alcohol is injected directly into tumors, either through the skin or during an operation. Alcohol dries out the cells of the tumor and eventually the cells die. Each treatment consists of one injection, although you may need a series of injections for the best results. Alcohol injection has been shown to improve survival in people with small hepatocellular tumors. It may also be used to help reduce symptoms in cases of metastatic liver cancer. The most common side effect is leaking of alcohol onto the liver or into the abdominal cavity.

Surgery is increasingly being used for patients with secondary liver cancer. This can sometimes involve removing a segment of liver. Alternatively, keyhole techniques can be used to apply extreme cold or heat to localized areas of the liver.

By: User name – Peter Hutch

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Liver Cancer – Diagnosis, Causes, Symptoms,treatment And Prognosis.

Liver cancer also known as primary or metastatic hepatic carcinoma is a fairly rare form of cancer in the western world (1% of all cancers) but much more common in Africa and parts of Asia (10% to 50% of all cancers). It is much more prevalent in men and incidence increases with age. Liver cancer is rapidly fatal, usually within 6 months from gastrointestinal hemorrhage, hepatic failure or metastasis.

TYPES OF LIVE CANCER
Most primary liver tumors are known as hepatomas (hepatocellular carcinoma and primary lower cell carcinoma). Some primary liver cancers originate in the bile duct and these are known as cholangiomas. Some rare liver cancers include Kupffer cell sarcoma and hepatoblastomas (which occur almost exclusively in children and are usually respectable and curable). Metastatic liver cancer is 20 times more common than primary liver cancer and after cirrhosis this is the leading form of liver related death.

SIGNS AND SYMPTOMS
Liver cancer does not normally cause symptoms until it is in an advanced stage.
Clinical effects of advanced liver cancers include:
1.A mass in the right upper side.
2.Tender, nodular liver on palpation
3.Severe pain in the epigastrium or upper right side
4.Weight loss, anorexia, weakness, fever
5.Occasional jaundice or ascites (fluid in the abdomen)

CAUSOF LIVER CANCER
The exact cause of liver cancer is unknown in adults but in children it may be a genetic disease. Adult liver carcinomas may result from environmental exposure to carcinogens such as mold, contrast media (no longer in use), androgens and oral estrogens, the hepatitis B virus or by damage to the liver due to cirrhosis caused by too much prolonged imbibing of alcohol.

DIAGNOSIS
Liver cancer is difficult to diagnose in the presence of cirrhosis, but several tests can help identify it: The combination of an imaging study (ultrasound, CT, or MRI scans) and an elevated blood level of alpha-fetoprotein will most effectively diagnose liver cancer, electrolyte studies may indicate increased sodium retention, a liver biopsy can make a definitive diagnosis.

TREATMENT
Treatments for primary liver cancer depend on the extent (stage) of the disease, age, overall health, feelings and personal preferences. Surgery is the most effective treatment for primary liver cancer, but this is not always possible due to the size or position of the tumor. Radiofrequency ablation is an option for people with small, unresectable hepatocellular tumors and for some types of metastatic liver cancers. During this procedure, the hepatic artery (the artery from which liver cancers derive their blood supply) is blocked, and chemotherapy drugs are injected between the blockage and the liver. Cryoablation may be an option for people with inoperable primary and metastatic liver cancers. Removing the whole liver and replacing it with a liver from another person is another possible form of treatment for primary liver cancer.

Even when treatments fail to provide much improvement in the liver cancer itself, pain and other signs and symptoms caused by liver cancer can be aggressively treated to improve quality of life. In general, the treatments available for children are the same as for adults, and the best approach depends on the stage and type of cancer as well as the child’s age and overall health.

PROGNOSIS
Prognosis is poor when cancer is advanced, but for small tumors that are confined to the liver, ablative therapies are palliative and surgical resection or liver transplantation is sometimes curative.

By: Dick Aronson

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